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. Author manuscript; available in PMC: 2011 May 10.
Published in final edited form as: Nature. 2004 Aug 5;430(7000):631–639. doi: 10.1038/nature02621

Figure 3. Strategies and targets for the prevention and treatment of AD.

Figure 3

Approaches that are being tested in clinical and/or primary prevention trials include Aβ immunization, Cu+/Fe2+ chelation, cholesterol-lowering drugs (statins), anti-inflammatory agents, antioxidants and folic acid. Epidemiological and animal studies suggest the potential benefits of cognitive stimulation, regular physical exercise and dietary restriction, but these remain to be critically examined in controlled prospective studies or clinical trials.