Table 4.
Day 5% of CD45+ Cells |
Day 100 % of CD45+ Cells |
|||||
---|---|---|---|---|---|---|
Group | No. | LEW Class I (LEW Class II) |
BN Class I | No. | LEW Class I (LEW Class II) |
BN Class I |
0. Normal heart | 8 | 98.7 ± 1.17 (24.9 ± 4.7) | NT | 8 | 98.7 ± 1.17 (24.9 ± 4.7) | NT |
1. Isograft control | 6 | 98.6 ± 0.7 (28.7 ± 4.4) | 0.6 ± 0.3 | 3 | 99.2 ± 0.4 (29.2 ± 0.2) | 0.8 ± 0.2 |
2. No treatment | 5 | 3.0 ± 0.9 (1.8 ± 0.5) | 97.4 ±1.0 | NA | NA | NA |
3. Short TAC | 5 | 28.6 ± 6.1 (3.3 ± 0.2) | 69.4 ± 2.6 | 3 | 2.0 ± 0.8 (<1.0) | 98.2 ± 0.9 |
4. Long TAC | 5 | 28.6 ± 6.1 (3.3 ± 0.2) | 69.4 ± 2.6 | 3 | 30.5 ± 7.4 (4.3 ± 1.6) | 69.0 ± 9.0 |
5. BMC prime | 6 | 2.5 ±1.1 (1.7 ± 0.4) | 97.8 ± 0.9 | 3 | 1.2 ± 0.7 (<1.0) | 98.2 ± 1.0 |
6. Liver TX prime | 5 | 22.0 ± 7.6 (9.2 ± 3.9) | 79.3 ± 8.7 | 3 | 8.4 ± 2.4 (2.0 ± 0.5) | 92.0 ± 2.8 |
NOTE. DC-rich subset of L21-6+ LEW cells is in parentheses. Normal heart data from naïve animals that did not undergo transplantation.
Abbreviations: TX, transplantation; NA, not applicable; NT, not tested.