Table 5.
Percentage Contribution of CDllb/c+ Cells to the Leukocyte (CD45+) Population in the Cell Suspensions Shown in Table 3
| Day 5 |
Day 100 |
|||||||
|---|---|---|---|---|---|---|---|---|
| Group | No | Total CDllb/c+ |
LEW+ CDllb/c+ (LEW Class II+ CDllb/c+) |
BN+ CDllb/c+ |
No. | Total CDllb/c+ |
LEW+CDllb/c+ (LEW Class II+ CDllb/c+) |
BN+ CDllb/c+ |
| 0. Normal heart | 8 | 48.6 ± 7.0 | 48.6 ± 7.0 (14.6 ± 4.6) | NT | 8 | 48.6 ± 7.0 | 48.6 ± 7.0 (14.6 ± 4.6) | NT |
| 1. Isografr control | 6 | 50.1 ± 11.2 | 48.9 ± 12.4 (21.6 ± 4.5) | 0.5 ± 0.3 | 3 | 45.3 ± 0.3 | 45.1 ± 0.1 (23.4 ± 1.9) | 0.2 ± 0.1 |
| 2. No treatment | 5 | 57.9 ± 12.2 | 1.7 ±0.5 (1.3 ±0.1) | 56.2 ± 11.7 | NA | NA | NA | NA |
| 3. Short TAC | 5 | 69.4 ± 2.6 | 17.8 ±0.1 (2.3 ±0.1) | 51.6 ± 2.7 | 3 | 33.0 ± 7.2 | 1.5 ± 0.4 (<1.0) | 31.5 ± 6.9 |
| 4. Long TAC | 5 | 69.4 ± 2.6 | 17.8 ±0.1 (2.3 ±0.1) | 51.6 ± 2.7 | 3 | 51.0 ± 11.3 | 25.2 ± 8.0 (1.4 ± 0.1) | 25.8 ± 4.3 |
| 5. BMC prime | 6 | 17.6 ± 6.1 | 3.3 ± 1.8 (1.0 ± 0.2) | 14.3 ± 4.4 | 3 | 37.2 ± 7.4 | 1.6 ± 0.2 (<1.0) | 31.8 ± 4.8 |
| 6. Liver TX prime | 5 | 36.8 ± 10.0 | 13.8 ± 5.8 (5.8 ± 3.8) | 23.0 ± 5.2 | 3 | 30.7 ± 7.9 | 5.9 ± 1.3 (1.7 ± 0.2) | 24.8 ± 9.2 |
NOTE. LEW cells that contribute to the total CDllb/c+ population in all allograft groups are shown separately; DC-rich subset of L21-6+ LEW cells that also are CDllb/c+ is in parentheses. All numbers are shown as percentage of CD45+ cells. Normal heart data from naïve animals that did not undergo transplantation.
Abbreviations: TX, transplantation; NA, not applicable; NT, not tested.