Table 3.

Quantitative trait loci for craniofacial traits in Fels Longitudinal Study participants^*.

Trait	N	$h_r^2$	$h_q^2$	LOD	P**	Chromosome	cM***	Cytogenetic location	#BP in 1-LOD Interval	#Genes in 1-LOD Interval	Component
Lower facial height	618	0.0+0.10****	0.553	3.35	0.011	3	84	3p21.31-p14.1	16,960,012	192	Splanchnocranial
Gonial Angle	573	0.0+0.10	0.506	3.37	0.014	6	22	6p25.1-p24.1	5,338,303	30	Splanchnocranial
LE - Occ	237	0.0+0.17	0.747	3.27	0.019	6	22	6p25.3-p24.1	12,718,164	71	Soft tissue
Facial Taper	654	0.0+0.09	0.496	3.52	0.007	6	23	6p25.1-p24.1	5,501,288	33	Splanchnocranial
Post. Facial Ht	573	0.0+0.11	0.563	4.52	0.0008	6	106	6q16.1-q21	16,146,101	47	Splanchnocranial
S-X80	587	0.0+0.10	0.502	3.24	0.020	6	121	6q16.3-q22.33	26,595,994	119	Neurocranial
S-X70	587	0.0+0.10	0.515	2.89	0.048	6	122	6q16.3-q23.2	27,699,629	124	Neurocranial
N-Pt.A	614	0.0+0.10	0.461	3.14	0.029	11	49	11p15.1-q12.1	58,193,54	221	Splanchnocranial
Ba-N	611	0.0+0.10	0.429	3.11	0.023	12	75	12q13.11-q21.31	35,563,317	363	Basicranial
NeuroPC2	587	0.0+0.11	0.455	3.22	0.021	14	76	14q21.3-q31.3	39,665,099	255	Neurocranial

^*Maximum likelihood heritability estimates from linkage models: $h_q^2$ is the QTL-specific heritability, i.e., the proportion of the residual phenotypic variance due to the effect of the QTL, and $h_r^2$ is the residual heritability, i.e., the proportion of the phenotypic variance in the trait due to the effects of genes other than the QTL.

^**Genome-wide P-value associated with LOD score calculated using a modification of a method suggested by (Feingold et al. 1993) that takes into account pedigree complexity and the finite marker density of the baboon whole linkage map used in these analyses.

^***Location in centimorgans (cM) from pter-most marker locus in human genetic linkage map for that chromosome.

^****Standard errors for maximum likelihood estimates of residual $h^2(h_r^2)$ that estimated on a boundary (e.g., 0) were obtained by interpolative maximization.