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. 2011 Jun 1;138(11):2185–2196. doi: 10.1242/dev.058347

Fig. 2.

Fig. 2.

Numb-TS4D specifically affects type II neuroblasts. (A) Ectopic neuroblasts induced by Numb-TS4D are Asense negative (Ase−, red) and Miranda positive (Mira+, blue). Magnified regions are boxed and shown in the right panels (Aa′,Ab′). (B) Specific expression of Numb-TS4D in type II neuroblasts using Dll-Gal4 leads to ENF (Bd), whereas neuroblast number is not affected when Numb-TS4D is expressed in type I neuroblasts using asense-Gal4 (Bb). (C,D) Clonal analysis of Numb-TS4D effect on type II neuroblast homeostasis. Wild-type or Numb-TS4D-expressing MARCM clones are marked with GFP (green). Numb-TS4D has no effects on Ase+ Mira+ type I neuroblast (Cb), but induced ectopic Ase− Mira+ type II neuroblasts (Db, labeled as asterisks). Scale bars: 20 μm in A,B; 10 μm in C,D.