Skip to main content
. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Mutat Res. 2011 Feb 15;708(1-2):59–68. doi: 10.1016/j.mrfmmm.2011.02.001

Fig. 4.

Fig. 4

Mili-KO MEFs exhibit high sensitivity to cisplatin and deficient NER for removing cisplatin-induced intrastrand crosslinks. (A) Mili-WT and KO MEFs were treated with cisplatin for 1 h, further cultured for the indicated time periods. The initial and remaining Pt-GG level were detected by ISB assay with anti-Pt-GG antibody (Bars: SD, n=3). (B) WT and Mili-KO MEFs were treated with cisplatin for 1 h. The cells were further cultured in drug-free medium for 5 days. The relative survival of cells was determined by methylene blue staining (Bars: SD, n=4).