Figure 4.

Expression profiles for regulated genes, sharing enriched annotation categories, during zinc depletion. Gene expression in gills at 0.3, 1, 4, 7, and 14 days of zinc depletion is given as fold-change ranging from -4 (green) to +4 (red, see colour bar) relative zinc adequate control fish. Gene trees were generated using Pearson Correlation and Average Linkage Clustering. The represented categories are (A) 'anatomical structure morphogenesis', (B) 'neuron differentiation', (C) 'nucleus', (D) 'Protein-tyrosine phosphatase, Tyr-specific/dual-specificity type', (E) 'nucleobase, nucleoside and nucleotide metabolic process', (F) 'regulation of neurotransmitter levels', and (G) 'cellular lipid metabolic process' as detailed in Figure 3.