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. 2010 Oct 8;11:548. doi: 10.1186/1471-2164-11-548

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Copyright ©2010 Zheng et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Frequency of transcription factor binding sites (TFBS) to Foxl1 and Mtf1 among regulated genes. The binding sites are located within 2000 bp DNA sequence upstream the ATG of genes that were regulated by zinc depletion at different time-points. TFBS to Foxl1 and Mtf1 were present in 90.4% and 18.7%, respectively, of 198 randomly selected control genes that showed stable expression throughout the experiment. A significant difference relative to that in the control genes is indicated by an asterisk (P < 0.05, z-test).