Table 2.
Functional categories of genes that significantly contribute to PC1 and PC2.
| Function | P value | Screened members | Total members | Gene names |
|---|---|---|---|---|
| PC 1 top 5% | ||||
| Galactitol metabolic process | 5.98E-06 | 4 | 4 | gatB, gatC, gatY, gatZ |
| Phosphate transport | 3.58E-07 | 6 | 8 | phoB, phoU, pstA, pstB, pstC, pstS |
| Phosphoenolpyruvate-dependent sugar phosphotransferase system | 3.01E-04 | 6 | 20 | dhaH, gatB, gatC, manX, manY, manZ |
| Response to stress | 9.57E-06 | 13 | 64 | clpB, degP, dnaK, grpE, hslJ, hslU, htpG, ldhA, pstS, uspG, relB, relE, yfiA |
| Response to heat | 1.16E-05 | 8 | 24 | dnaK, groL, groS, grpE, hslJ, hslU, htpG, ldhA |
| Protein folding | 1.64E-05 | 8 | 25 | degP, dnaK, dsbA, groS, groL, grpE, htpG, ppiA |
| PC 1 bottom 5% | ||||
| Cellular amino acid biosynthetic process | 3.73E-08 | 20 | 100 | argF, argI, aroF, aroM, carA, carB, hisA, hisB, hisC, hisD, hisF, hisG, hisH, hisI, leuL, lysC, metH, pheA, thrL, trpL |
| Histidine biosynthetic process | 4.53E-09 | 8 | 11 | hisA, hisB, hisC, hisD, hisF, hisG, hisH, hisI |
| Arginine biosynthetic process | 3.00E-03 | 4 | 13 | argF, argI, carA, carB |
| Tricarboxylic acid cycle | 4.05E-04 | 6 | 21 | fumA, mqo, sdhA, sdhB, sdhC, sdhD |
| Transport | 1.21E-04 | 33 | 351 | amtB, argT, betT, emrA, entD, fadL, fiu, kgtP, livF, livG, livH, livJ, livK, livM, modA, modB, ompF, oppA, oppB, oppC, oppD, oppF, proP, putP, rbsB, rfbX, sdhA, sdhB, sdhC, sdhD, tsx, uraA, yhbE |
| Amino acid transport | 1.63E-03 | 8 | 46 | putP, argT, livF, livG, livM, livH, livK, livJ, |
| Peptide transport | 1.91E-03 | 5 | 19 | oppA, oppB, oppC, oppD, oppF |
| Flagellum organization | 4.72E-04 | 3 | 4 | flgC, flgD, flhM |
| PC 2 top 5% | ||||
| Cellular amino acid biosynthetic process | 1.49E-10 | 23 | 100 | argH, aroF, carB, hisB, hisC, hisD, hisH, ilvA, ilvB, ilvC, ilvD, ilvE, ilvM, leuA, leuB, leuC, leuD, trpB, trpC, trpD, trpE, trpL, tyrA |
| Histidine biosynthetic process | 1.50E-03 | 4 | 11 | hisB, hisC, hisD, hisH |
| Tryptophan biosynthetic process | 1.67E-06 | 5 | 6 | trpB, trpC, trpD, trpE, trpL |
| Branched-chain family amino acid biosynthetic process | 9.76E-10 | 10 | 17 | ilvA, ilvB, ilvC, ilvD, ilvE, ilvM, leuA, leuB, leuC, leuD |
| Iron ion transport | 5.47E-17 | 18 | 30 | cirA, entA, entB, entC, entD, entE, entF, fecA, fecB, fecI, fecR, fepA, fepB, fepC, fes, fhuE, fiu, mntH |
| Enterobactin biosynthetic process | 6.62E-10 | 7 | 7 | entA, entB, entC, entD, entE, entF, ybdB |
| Iron-sulfur cluster assembly | 1.05E-04 | 5 | 11 | hscA, iscS, sufA, sufB, sufD |
| PC 2 bottom 5% | ||||
| Lipopolysaccharide biosynthetic process | 2.70E-06 | 12 | 49 | eptB, kdtA, htrL, rfaB, rfaC, rfaF, rfaG, rfaI, rfaP, rfaQ, rfaS, rfaY |
| Dipeptide transport | 8.29E-05 | 4 | 6 | dppB, dppC, dppD, dppF |