Table 2.
Comparision of the key families and genes involved in apoptosis in mammals, Drosophila, Nematode, Echinoids, silkworm and fish.
| Species name Families/genes'name | Mammala | Fruit Fliesb | Nematodec | Echinoidsd | Silkworme | Fishf |
|---|---|---|---|---|---|---|
| TNFSFA | 50 | 2 | 0 | 11 | 2 | 11 |
| Caspase FamilyB | 13 | 7 | 4 | 34 | 5 | 12 |
| Bcl-2 FamilyC | about 20 | 2 | 3 | 10 | 1 | 13 |
| Bir DomainD | 7 | 4 | 2 | 7 | 4 | 5 |
| RHGE | 0 | 4 (each1) | 0 | 0 | 1 (reaper) | 0 |
| P53F | 1 | 1 | 1 | 1 | 1 | 1 |
| Apaf-1G | 1 | 1 | 1 | 1 | 1 | 1 |
In this study Homo sapiens represents mammals, Drosophila melanogaster represents fruit flies, Caenorhabditis elegans represents nematodes, Strongylocentrotus purpuratus represents Echinoids, Bombyx mori represents silkworms, and Danio rerio represents fish. The TNF family comprised of the ligands and the correspondent receptor. aA data are from [76-78]; aB data are from [79]; bB, cB, bC and cC data are from [65] and [6]; dA-dD and fA-fC data are from [80] and [81], respectively. The other data are the results of BLAST searches with the database in NCBI.