Table 4.

Differentially expressed proteins identified by MALDI-TOF-MS/MS analysis of 2D gel protein profiles of iBMDCs treated with [BF/S+L/Ep] (75 ug/mL) in vitro for 12 h

Spot Number	Protein Name	Relative Protein Level a	SwissProt Accession Number	Biological Function
54	Annexin A4	1.73	P97429	Signal transduction; cell communication
34	Peroxiredoxin 4	1.56	O08807	Metabolism; Energy pathways
82	Vimentin	1.13	P20152	Cell growth/maintenance
26	Alpha-actin-2	1.12	P62739	Cell growth/maintenance
23	Proliferin-1	1.1	P04095	Cell growth/maintenance
98	APAF1-interacting protein	1.09	Q9WVQ5	apoptosis
1	beta-actin	1.05	P99041	Cell growth/maintenance
58	Alpha-tubulin 1, 2, 4, 6	1.04	P68369...	Cell growth/maintenance
79	Heat shock cognate 71 kDa protein	1.04	P63017	Protein metabolism
109	Solute carrier family 35 member E1	1.04	Q8CD26	Transport
55	Actin, cytoplasmic 1 (Beta-actin)	1.03	P60710	Cell growth/maintenance
88	YEATS domain-containing protein 4	0.96	Q9CR11	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
6	Phenylalanyl-tRNA synthetase	0.92	Q99M01	Protein metabolism
41	Protein disulfide-isomerase A3 [Precursor]	0.92	P27773	Protein metabolism
38	Phosphoglycerate mutase 1	0.87	Q9DBJ1	Metabolism; Energy pathways
78	Heat shock protein 9, [Precursor]	0.84	P38647	Protein metabolism
56	F-actin capping protein alpha subunit	0.83	P47754	Cell growth/maintenance
13	Cathepsin S	0.81	O70370	Protein metabolism
91	Nucleoside diphosphate kinase	0.74	Q9WV84	Metabolism; Energy pathways
70	Alpha-enolase	0.73	P17182	Metabolism; Energy pathways
45	Macrophage capping protein	0.63	P24452	Cell growth/maintenance
192	Voltage-gated potassium channel subfamily KQT member 2	0.46	Q9Z351	Transport
191	Protein tyrosine phosphatase mitochondrial 1	0.34	Q66GT5	signal transduction; cell communication

^a Relative protein level with or without [BF/S+L/Ep] (75 μg/mL), 0.1% DMSO as vehicle control.