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Highly conserved residues shared by 66 cluster-associated (including those from 49 novel clusters) lanthionine cyclases. Residues are numbered according to their position in NisC
| Conserved Residues | NisC Position | % Conservation |
|---|---|---|
| Motifs | ||
| LxxG | 39-42 | 83% |
| YDxxxGxxG | 140-148 | 67% |
| GxAHGxxG | 209-216 | 83% |
| WCYG | 283-286 | 95% |
| CHG | 330-332 | 98% |
| GxxxGxxGxxLxL | 377-389 | 73% |
| Single Residues | ||
| G | 90 | 94% |
| W | 258; 401 | 83%; 92% |
