Table 1. Distribution of Cre-positive cell types in P28 Plp-Cre CNS tissues.
% of CC-1+cells that are Cre+a | % of Cre+cells that are CC-1+a | % of Cre+cells that are Ng2+ | % of Cre+cells that are GFAP+a | % of Cre+cells that are NeuN+ | |
Spinal Cord | 88.9%±5.4 | 95.8%±6.8 | 10.8%±0.7 | 10.6%±2.2 | 0 |
Cerebellum | 86.0%±4.8 | 90.0%±9.2 | 5.8%±4.3 | 8.6%±5.8 | 0 |
Optic Nerve | 91.2%±6.4 | 88.7%±2.8 | 3.8%±2.5 | 3.3%±0.2 | n.d. |
There are most likely Cre-positive cells which stain for GFAP and CC-1. These cells are assumed to be GFAP astrocytes, and not oligodendrocytes.
n.d. = not determined