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Effects of fenofibrate on IL-6 protein levels in brain (A) and serum (B) measured by ELISA at 6 hours after LPS injection. V, vehicle; W, Wy-14643 at 30 mg/kg; F, fenofibrate at 30 mg/kg. Experiments were done in 5 animals in each group. Data are shown as mean + SD. *P<0.05, **P<0.01 and ***P<0.001 compared to saline-injected group; ##P<0.01 compared to vehicle-treated LPS-injected group. Statistical analysis was made by one-way ANOVA followed by Scheffe post-hoc test.
