Table IV.
Multivariable Models Indicating Independent Determinants of Cardiac Structure and Function
| Variable | LVMI | RWT | E/A Ratio | E/Ea Lateral Ratio | E/Ea Septal Ratio | Ea/Aa Lateral Ratio | Ea/Aa Septal Ratio | Average Lateral and Septal Ea/Aa Ratios | E/Average Ea Lateral and Septal |
|---|---|---|---|---|---|---|---|---|---|
| Intercept | 3.21 | 0.20 | 5.49 | 4.34 | 6.65 | 10.68 | 7.51 | 35.49 | 5.86 |
| BP category | |||||||||
| NT | −0.06 | −0.45 | −0.46 | ||||||
| Pre‐HTN | −0.063 | −0.38 | −0.29 | ||||||
| HTNa | 0 | 0 | 0 | ||||||
| Age | 0.0047 | −0.026 | −0.044 | ||||||
| Female | −0.1 | −0.010 | |||||||
| Non‐white race | −0.58 | 0.27 | |||||||
| T2DM | −0.16 | 0.44 | 0.64 | −0.68 | 0.52 | ||||
| BMI z score | 0.075 | 0.13 | 0.50 | −1.61 | −0.11 | 0.37 | |||
| Waist/height ratio | 0.88 | 0.12 | −1.08 | 2.95 | −1.81 | ||||
| MAP | −0.54 | −1.25 | −0.81 | −4.27 | |||||
| Heart rate | −0.0033 | −0.010 | −0.017 | −0.011 | |||||
| LDL‐C | −0.008 | ||||||||
| HDL‐C | 0.016 | ||||||||
| TG | 0.010 | ||||||||
| Fasting glucose | |||||||||
| Fasting insulin | −0.108 | ||||||||
| CRP | 0.08 | ||||||||
| R 2 | 0.52 | 0.1 | 0.12 | 0.16 | 0.17 | 0.19 | 0.3 | 0.2 | 0.21 |
Abbreviations: BMI, body mass index; BP, blood pressure; CRP, C‐reactive protein; HDL‐C, high‐density lipoprotein cholesterol; HTN, hypertension; LDL‐C, low‐density lipoprotein cholesterol; LVMI, left ventricular mass index; MAP, mean arterial pressure; NT, normotension; RWT, relative wall thickness; T2DM, type 2 diabetes mellitus; TG, triglycerides. a0 indicates HTN group treated as reference group. All models have P<.0001 except Ea/Aa septal P<.007, and all parameter estimates listed have P<.05.