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. 2010 May;1(5):444–464. doi: 10.1177/1947601910376079

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Figure 8. — Gene Ontology (GO) enrichment pathway analysis. Analysis of genes modulated following PRKCZ-ζ knockdown identified 4 pathways principally affected: (A, B) genes known to be regulated by NFKB and almost universally down-regulated and (C, D) gene networks linked to KDMSB, MCM6, and DDIT3. This analysis revealed that some of the genes modulated by down-regulated expression of PRKC-ζ are interconnected, emphasizing the numerous pathways for cross-talk between apparently distinct biological processes.