Table 6.
Accuracy of fused-lasso minimization for various SNP sequence lengths. For strategy (a), average values of λ1 and λ2 specified for each individual are summarized for each SNP sequence length; Standard errors appear in parentheses
| Sequence length | λ 1 | λ 2 | TPR (%) | FPR (%) | FDR (%) |
|---|---|---|---|---|---|
| (a) λ1 and λ2 specified for each individual according to equation (11) | |||||
| 4000 | 0.13 (0.04) | 0.73 (0.23) | 88.40 | 0.0414 | 6.73 |
| 8000 | 0.13 (0.04) | 0.76 (0.24) | 89.54 | 0.0241 | 7.66 |
| 12,000 | 0.12 (0.03) | 0.76 (0.16) | 90.85 | 0.0148 | 7.00 |
| 16,000 | 0.13 (0.04) | 0.79 (0.22) | 87.63 | 0.0103 | 6.77 |
| 20,000 | 0.13 (0.04) | 0.80 (0.22) | 85.34 | 0.0084 | 7.07 |
| Overall | − | − | 88.35 | 0.0145 | 7.05 |
| (b) Oracle choice of λ1 and λ2: constant values across all individuals | |||||
| 4000 | 0.16 | 0.80 | 83.70 | 0.0414 | 7.08 |
| 8000 | 0.19 | 0.80 | 77.46 | 0.0206 | 7.58 |
| 12,000 | 0.18 | 0.180 | 84.09 | 0.0141 | 7.20 |
| 16,000 | 0.17 | 0.90 | 81.12 | 0.0102 | 7.20 |
| 20,000 | 0.18 | 0.180 | 76.12 | 0.0077 | 7.26 |
| Overall | − | − | 80.50 | 0.0136 | 7.26 |