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. Author manuscript; available in PMC: 2011 May 11.
Published in final edited form as: Ann Appl Stat. 2010 Dec 1;4(4):1749–1773. doi: 10.1214/10-AOAS357

Table 7.

Accuracy of DPI for various SNP sequence lengths. For strategy (a), average values ofλ1 and λ2 specified for each individual are summarized for each SNP sequence length; Standard errors appear in parentheses

Sequence length λ 1 λ 2 TPR (%) FPR (%) FDR (%)
(a) λ1 and λ2 specified for each individual according to equation (11)
4000 0.13 (0.04) 0.73 (0.23) 93.70 0.0013 0.22
8000 0.13 (0.04) 0.76 (0.24) 93.33 0.0007 0.22
12,000 0.12 (0.03) 0.76 (0.16) 95.78 0.0004 0.22
16,000 0.13 (0.04) 0.79 (0.22) 94.77 0.0009 0.56
20,000 0.13 (0.04) 0.80 (0.22) 92.32 0.0005 0.43
Overall 93.98 0.0007 0.33
(b) Oracle choice of λ1 and λ2: constant values across all individuals
4000 0.15 2.50 87.72 0.0013 0.22
8000 0.24 2.70 86.35 0.0007 0.25
12,000 0.12 0.0 94.43 0.0004 0.22
16,000 0.18 2.10 91.51 0.0009 0.60
20,000 0.16 20,00 90.18 0.0005 0.41
Overall 90.04 0.0007 0.34