Table 7.

Suggested regimen for the reintroduction of anti-tuberculosis drugs following drug-induced hepatitis ³⁵

	Isoniazid		Rifampicin		Pyrazinamide
	Adult	Child	Adult	Child
Day 1	150mg	5mg/kg	Omit	Omit	Omit
Day 2	150mg	5mg/kg	Omit	Omit	Omit
Day 3	300mg	10mg/kg	Omit	Omit	Omit
Day 4	300mg	10mg/kg	150mg	5mg/kg	Omit
Day 5	300mg	10–20mg/kg	300mg	5mg/kg	Omit
Day 6	300mg	10–20mg/kg	450mg	10mg/kg	Omit
Day 7	300mg	10–20mg/kg	450mg (<50kg)600mg (>50kg)	10–20mg/kg	Consider reintroduction if normal liver function after 14 days of full doserifampicin and isoniazid. If pyrazinamide not used, treat for 18months