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. 2011 May 9;208(5):1093–1103. doi: 10.1084/jem.20101527

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Figure 1. — KLF13 is critical for the maintenance of CD4⁻CD8⁺CD24⁻ T cells in BALB/c thymus. (A) CD4 and CD8 expression in thymocytes from wild-type and Klf13^−/− BALB/c mice. (B) Absolute numbers of CD4⁺CD8⁻ single positive (CD4⁺ SP) and CD4⁻CD8⁺ (CD8⁺ SP) cells in the thymi of wild-type and Klf13^−/− BALB/c mice. P < 0.05 is considered significant. Error bars are SDs. (C) Purified CD4⁺CD8⁺ double-positive (DP) cells were differentiated with PMA, ionomycin, and IL-7 to CD8⁺ SP cells in vitro. (D) Expression of CD24 and TCRβ in the indicated thymic populations from BALB/c and C57BL/6 mice. Gates were based on an isotype control antibody. (E) Expression of CD44 and CD62L in CD4⁺ SP and CD8⁺ splenocytes from BALB/c mice. Data are representative of three (B and C) and four (A, C, and E) independent experiments with three mice in each genotype group.