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. 2011 May 9;208(5):1105–1117. doi: 10.1084/jem.20101831

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© 2011 Pyzik et al.

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Figure 6. — Adoptive transfer of naive Ly49L⁺ NK cells into BALB.K neonates improves their survival after MCMV infection. (A) Adoptive transfer scheme. (B) Sorting gate position and purity. (C) Survival of BALB.K neonate mice receiving Ly49L⁺ NK cells (1 × 10⁴, 4 × 10⁴, or 7 × 10⁴), Ly49L⁻ NK cells (7 × 10⁴), total MA/My NK cells (1 × 10⁵), or PBS as a control, followed by MCMV infection at a dose of 1,000 PFU/pup. Data represent four pooled experiments. (D) Viral titers at day 3 p.i. in neonate pups transferred with 1 × 10⁵ of either Ly49L⁺ or Ly49L⁻ NK cells or PBS only (median viral titer ± IQR). Three pups per condition were tested. Data represent one of two experiments performed.