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. Author manuscript; available in PMC: 2011 May 11.
Published in final edited form as: J Mol Cell Cardiol. 2010 Nov 6;50(1):147–156. doi: 10.1016/j.yjmcc.2010.10.034

Figure 7. Acute VO alters the distribution of subsarcolemmal mitochondria (SSM) interstitial collagen, and integrin α5 in LV.

Figure 7

Sections of LV tissue are stained with collagen I and III, CcOX4, and integrin α5 (Intg α5) antibodies using fluorescent microscopy. There is loss of collagen I and III, CcOX4, and Intg α5 that is restored by PD 166793 and infliximab (Panel A). In Panel B, overlay of collagen I and III and Intg α5 with CcOX4 and DAPI at higher power demonstrates a prominent loss of CcOX4 and Intg α5 in the subsarcolemmal area of cardiomyocytes in the ACF LV, which is restored by PD 166793.