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. Author manuscript; available in PMC: 2011 May 11.
Published in final edited form as: Circulation. 2010 Sep 27;122(15):1488–1495. doi: 10.1161/CIRCULATIONAHA.109.921619

Table 2.

MRI-derived indices of LV remodeling in Normal and 4 month MR dogs.

Normal MR MR+CI
LV end-diastolic volume, mL 58±3 83±10 * 87±10*
LV end-systolic volume, mL 38±2 48±6 51±7
LV stroke volume, mL 20±2 35±5 * 36±4 *
LV ejection fraction, % 34±2 44±2 * 42±3 *
LV end-diastolic dimension, cm 3.6±0.2 4.3±0.1 * 4.3±0.2 *
LV end-systolic dimension, cm 3.3±0.1 3.6±0.1 * 3.6±0.2 *
Left atrial volume, mL 144±1 340±75 * 344±64 *
LV early diastolic filling rate (ml/sec) 148±24 240±48 269±48
LV early diastolic filling rate (EDV/sec) 2.5±0.4 2.9±0.5 3.2±0.4
Peak early mitral annular velocity (mm/sec) 30±3.5 30±12 52±14
Peak early mitral annular velocity (% LA length/sec) 53±6 48±20 81±22
Normalized Peak LV Systolic Torsion Angle (°) 2.54±0.84 3.15±0.36 4.16±0.31 *#
Sample Size, n 7 9 8

Values are mean ± SEM

*

P < 0.05 indicates significant difference from Normal group

#

P < 0.05 indicates significant difference from MR group

LA = Long axis