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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Behav Brain Res. 2011 Mar 4;221(1):237–245. doi: 10.1016/j.bbr.2011.02.045

Figure 1.

Figure 1

a) Time lines and visual stimuli presented during the fear conditioning paradigm

We focused on three different phases of the experiment — delivered shock, non-delivered shock and safe-no shock conditions — each marked in hashed grey. In addition to the above stimuli, a stimulus with a yellow light, like the red light above, was also used for conditioning. Images are adapted from Milad et al, 2007.

b) Conditioning paradigm and galvanic skin conductance responses

The fear conditioning paradigm entailed 32 trials of three types: 10 conditioned cue presentations ending with a shock (delivered shock), 6 conditioned cue presentations ending without a shock (non-delivered shock) and 16 safe cue presentations never ending with a shock (safe-no shock). Normalized skin conductance responses from a single representative subject in three trials are indicated. Skin conductance rose slightly at the onset of the context, continued rising at the presentation of the cue (conditioned response), and displayed a prominent peak after the delivery of the shock (unconditioned response).

c) Unconditioned skin conductance responses to the delivered shock (red) and non-delivered shock (black) across the 16 CS+ trials.