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. Author manuscript; available in PMC: 2011 May 11.
Published in final edited form as: Circ Res. 2008 Mar 20;102(9):1127–1136. doi: 10.1161/CIRCRESAHA.107.163642

TABLE 1.

LV hemodynamics and echocardiography in control, 4W-MR, and 4W-MR+ β1-RB dogs

Control
(n=6)
4W-MR
(n=6)
4W-MR+β1-RB
(n=6)
Heart rate, bpm 94 ±6 86 ±6 83 ±5
Mean arterial pressure (mmHg) 84 ±3 65 ±4* 62 ±3*
LV end diastolic pressure (mmHg) 4 ±1 8 ±1 6 ±2
Systemic vascular resistance, dyne.s.cm−5 2007 ±219 1606 ±240 2342 ±176
Cardiac output, L/min 3.6 ±0.4 3.8 ±0.6 2.1 ±0.1*
LV mass, g/kg 4.4 ±0.2 5.0 ±0.3 5.0 ±0.2
LV end-diastolic dimension, % change 9.2 ±2.9 17.7 ±4.7
LV end-systolic dimension, % change −7.4 ±5.8 0.1 ±3.6
LV end-diastolic wall thickness, % change −12.0 ±8.5 −10.2 ±5.8
Wall thickness/end-diastolic dimension, % change −18.6 ±9.3 −20.9 ±6.5
Fractional shortening, % change 32.7 ±11.3 34.3 ±13.9

Values presented as mean±SEM.

*

P<0.05 vs control.

P<0.05, % change vs baseline study.