Fig. (5).

Histological thin sections after 8 weeks implantation (representative for both nanocomposites, surface stained with van Kossa). (a, b) New bone is formed within the resorption zone (arrow). (c) Macrophages arranged in circles resorb the (d) biomaterial and (e) fuse finally to foreign body giant cells. The resorption zone consists further of (f) osteoprogenitor cells. The absence of clusters of lymphocytes, plasma cells and fibrocytes confirmed the biocompatibility of the electrospun PLGA/CaP and PLGA/Ag-CaP nanocomposites.