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. Author manuscript; available in PMC: 2011 May 11.
Published in final edited form as: Clin Pharmacol Ther. 2008 Jan 9;84(1):111–118. doi: 10.1038/sj.clpt.6100476

Figure 4.

Figure 4

Association between the erythromycin breath test variable C20,min, and log-transformed unbound docetaxel, estimated from the final population pharmacokinetic model. The symbol (x), represents patients with normal liver function, and the symbols (□), (○), and (Δ) represent patients with liver function abnormalities in liver function groups 2, 3A, and 3B, respectively. The dashed line is a linear-regression analysis of data in patients with normal liver function (R2 = 0.03547; P = 0.177), and the solid line is from data in patients with liver function abnormalities (R2 = 0.603, P<0.0001).