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. Author manuscript; available in PMC: 2011 May 11.
Published in final edited form as: Anat Rec (Hoboken). 2009 Apr;292(4):580–586. doi: 10.1002/ar.20846

Figure 5.

Figure 5

PAR2 deficiency did not show effect on bleomycin-induced acute lung injury (7 days) in murine model. Wildtype (n = 8) and PAR2 −/− mice (n = 5) were IT exposed with bleomycin at dosage of 2 units/kg. Wildtype (n = 3) receiving IT saline were used as control. A. Extravascular lung water. The right lungs of the dead and the survival (sacrificed at 7 days) were removed to measure extravascular lung water. B. The level of hydroxyproline in the lung homogenate. C, D. Representative histological changes of bleomycin-induced acute lung injury. The left lungs were edematous, consolidate, hemorrhagic, and extensively infiltrated with inflammatory cells. Data were pooled in the 2 times of experiments. Data are mean ± SD.