Table 1.
Tumor/antibody combinations emphasized in the text
| Brain tumors discussed | Antibodies discussed | Target antigens | |||
| General type | Specific example | Name | How modified | Name | Unique to tumor? |
| glioma | GBMa | bevacizumab (Avastin) | humanized | VEGFc | No |
| lymphoma | PCNSLb | rituximab (Rituxan) | chimeric | CD20d | No |
| metastatic | breast cancer | trastuzumab (Herceptin) | humanized | Her2e | No |
a
GBM, glioblastoma multiforme
b
PCNSL, primary central nervous system lymphoma
c
VEGF, vascular endothelial growth factor
d
CD20, common B-cell antigen
e
Her2, human epidermal growth factor receptor 2