Table 2.

Summary of the V_H sequences derived from B cells of different isotypes in the cervix or peripheral blood

Summary	IgA		IgG1		IgG2		IgG3		IgM
	Cervix	Blood	Cervix	Blood	Cervix	Blood	Cervix	Blood	Cervix	Blood
Sequences Analyzed	48	48	48	48	48	48	48	48	64	64
Uniquea and Productiveb	38	41	30	40	26	35	22	28	40	56
Unique V-D-J Rearrangementsc	35	26	24	38	23	34	12	23	30	51

^aIdentical sequences of the same isotype were considered a single sequence.

^bA sequence was considered unique if it did not share 100% homology with another clone of the same isotype, and productive if it contained no stop codons.

^cThe number of different V-D-J combinations was determined considering only productive sequences and provides an indication of diversity when compared with the corresponding number of total unique productive sequences.