Table 1.
Frequency of promoter methylation for individual gene in ESCC patients (n = 47)
| Genes | Frequency of methylation (%) | p value | |
| ESCC | NT | ||
| p16 | 44.7% | 21.3% | 0.027 |
| p14 | 14.9% | 0.0% | 0.012 |
| DAPK | 46.8% | 12.8% | 0.001* |
| RAR-β | 46.8% | 12.8% | 0.001* |
| CDH1 | 42.6% | 21.3% | 0.046 |
| APC | 12.8% | 4.3% | 0.267 |
| TIMP3 | 14.9% | 2.1% | 0.059 |
| GSTP1 | 0.0% | 0.0% | N/A |
| MGMT | 12.8% | 4.3% | 0.267 |
| ADAM23 | 0.0% | 0.0% | N/A |
| RASSF1A | 14.9% | 4.3% | 0.158 |
| FHIT | 6.4% | 2.1% | 0.617 |
NT, non-tumor tissue; N/A, not available value;
*
statistical significance after multiple testing (p < 0.0042).