Table 1.

Probes more methylated in cytotrophoblasts than fibroblasts mapping to tumor suppressor genes

Gene symbol	Probe ID	Chr	CGI ID	Gene strand	Distance to TSS	Probe position relative to TSS	F Methylation level	C Methylation level	Difference in methylation between C and F	Difference in methylation between Pl and F
TP73	cg04391111	1	1	+	1125	Upstream	0.53	0.78	0.25	0.20
	cg25115460	1	1	+	37981	Downstream	0.39	0.06	−0.33	−0.19
	cg03846767	1	1	+	38163	Downstream	0.33	0.07	−0.26	−0.16
	cg26208930	1	1	+	38296	Downstream	0.64	0.11	−0.53	−0.19
RASSF5	cg17558126	1	1	+	629	Upstream	0.50	0.73	0.22	0.12
RASSF1	cg00777121	3	3	−	176	Downstream	0.60	0.83	0.22	0.17
	cg08047457	3	3	−	46	Upstream	0.66	0.94	0.28	0.20
	cg21554552	3	3	−	58	Upstream	0.52	0.88	0.37	0.21
APC	cg16970232	5	5	+	151	Upstream	0.55	0.76	0.21	0.19
	cg20311501	5	5	+	82	Upstream	0.46	0.67	0.22	0.21
	cg21634602	5	5	+	14	Upstream	0.50	0.75	0.25	0.20
	cg24332422	5	5	+	102	Downstream	0.43	0.72	0.29	0.25
	cg01240931	5	None	+	459	Downstream	0.59	0.86	0.27	0.17
DAB2IP	cg13060154	9	9	+	349	Downstream	0.55	0.91	0.35	0.20
	cg24794433	9	9	+	523	Downstream	0.73	0.96	0.22	0.19
	cg08128768	9	9	+	533	Downstream	0.68	0.96	0.28	0.21
PRKCDBP	cg05628549	11	11	−	155	Upstream	0.42	0.74	0.32	0.20
WT1	cg01693350	11	11	−	4900	Downstream	0.67	0.91	0.24	0.16
MORF4L1	cg03589001	15	15	+	458	Upstream	0.60	0.83	0.23	0.13

Genomic locations are based on NCBI genome build 36, March 2006. CGI ID is based on UCSC genome browser. Chr, chromosome; CGI, CpG island; TSS, transcription start site; F, fibroblasts; C, cytotrophoblasts; Pl, placenta.