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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: J Neuroimmunol. 2011 Apr 5;234(1-2):103–108. doi: 10.1016/j.jneuroim.2011.03.006

Figure 1.

Figure 1

Verification of chimerism. To verify irradiated congenic CD45.1 animals were chimeric following BM donation, whole blood was analyzed by flow cytometry for expression of CD45.2 and Pan CD45 expression. CD45+ cells from animals which received (A) WT or (B) CXCL10−/− BM were both approximately 90% positive for being CD45.2+ donor-derived cells. (C) Brain leukocytes categorized by low or high expression of CD45 (CD45LO or CD45HI respectively) were analyzed for CD45.2 expression as well with greater than 90% of CD45LO microglia (D) and CD45HI infiltrating leukocytes (E) being donor derived. Data is representative of two experiments with a total of six samples.