Fig 8.

CM promotes vascular cell proliferation, migration, survival and cord formation. The direct effects of control medium, CM + mouse IgG isotype control (mIgG) or CM +αMCP-1 MAb on cultures of HUVECs were examined in assays for proliferation (A), migration (B) and cord formation (C). Representative images of cord formation in HUVEC cultures (D). The effects of control medium, CM + mouse IgG isotype control (mIgG) or CM +αMCP-1 MAb on rat A7r5 smooth muscle cells were examined with respect to proliferation (E) and migration (F). Data are represented as mean ± S.E.M. Each condition was represented in triplicate. N= 3 experiments. *P < 0.05.