Table 1.
Size comparison of anatomical structures
| Body Measurements (N=6,P0) | Control Littermate | Pax2-Cre∷N-Myc CKO (mm) | P-Value*** | % Red |
|---|---|---|---|---|
| Trunk Width (shoulders) | 8.04+/-0.37** | 7.61+/-0.43 | 0.097 | 5.53% |
| Trunk Length (shoulder to hip) | 8.24+/-0.66 | 7.45+/-0.40 | 0.035 | 9.6% |
| *Inner Ear (Height) | 3.55+/-0.12 | 2.55+/-0.20 | 5.07×10-06 | 28.10% |
| *Inner Ear (Width) | 2.28+/-0.21 | 1.74+/-0.06 | 0.0013 | 23.54% |
| * Kidney (Height) | 3.55+/-0.38 | 2.37+/-0.07 | 0.00053 | 33.21% |
| * Kidney (Width) | 2.36+/-0.15 | 1.55+/-0.10 | 2.22×10-06 | 34.33% |
| Brain (Height) | 4.31+/-0.07 | 4.43+/-0.07 | 0.011 | (2.80%) |
| Brain (Width) | 7.95+/-0.38 | 7.69+/-0.34 | 0.24 | 3.30% |
| Heart (Height) | 3.94+/-0.26 | 3.93+/-0.12 | 0.96 | 0.01% |
| Heart (Width) | 3.77+/-0.80 | 3.65+/-0.79 | 0.79 | 3.3% |
| Inner Ear Measurements (N=1, 6 wk)* | % Red | |||
| Length BM | 6.73mm | 2.63mm | 61% | |
| WT (cubic μl) | MT (cubic μl) | |||
| Organ of Corti | 0.0101 | 0.00607 | 34% | |
| Basilar Membrane (BM) | 0.00728 | 0.00294 | 61% | |
| Tectorial Membrane | 0.0155 | 0.00423 | 73% | |
| Scala Vestibuli | 0.535 | 0.112 | 79% | |
| Scala Media | 0.348 | 0.0746 | 78% | |
| Scala Tympani | 0.437 | 0.189 | 57% | |
| SGN | 0.0448 | 0.0171 | 61% | |
*
Indicates area of Pax2 expression
**
Mean +/- Standard Deviation
***
Two-tailed Student T-Test