Table 1.

A summary of CNV frequencies in pharmacogenetic genes in different ethnic populations.

	CNV frequencies (%)
Population	CYP2D6*1×N	CYP2D6*2×N	CYP2D6*5	GSTM1 deletion	GSTT1 deletion
North America
U.S.A. (Caucasian)	0.2 [72]	0.7 [72]	6.2 [72]	54.3 [50]	27.6 [50]
U.S.A. (African-American)	1.2 [72]	1.6 [72]	4.0 [72]	23.7 [73]	17.5 [73]
Mexico (Mestizo)			1.3–2.7 [74, 75]	33.5 [76]	12.1 [76]
Africa
Cameroon	3.3 [26]	3.3 [26]		27.8 [51]	46.8 [51]
Ethiopia		10–16 [21, 77]	3.3 [77]	43.8 [51]	37.3 [51]
Ghana		1.6 [27]	6 [27]	19.3 [78]	73.7 [78]
East Asia
China ( Han)	2.2 [25]	0–2 [21]	7.2 [79]	52 [80]	38.7 [80]
Japan	0.5 [81]	0.5 [81]	6.2 [82]	50.8 [83]	45.8 [83]
Korea	0.13 [84]	0.5 [84]	6.1 [84]	51.4 [85]	51.6 [85]
Europe
France	2.0 [25]		4.0 [25]	49 [86]	26 [86]
Germany	0.51 [87]	1.34 [87]	1.95 [87]	51.6 [50]	19.5 [50]
Middle East
Saudi Arabia		10.4 [88]	1.0 [88]	8.3 [89]	4.2 [89]