Figure 2. TCRBV region gene usage in MBP-specific T-cells.
TCRBV gene usage by MBP-specific CD4+ and CD8+ T-cells from three healthy subjects (A-B) and three MS patients (C-D) is depicted. The X-axis represents unique TCRBV genes while the Y-axis plots the contribution of each gene (percentage) within the antigen-specific repertoire.