Table 2.
TCR repertoire of healthy MBP-specific CD8+ T-cells.
| Subject | BV locus |
CDR3 | BJ locus |
# | Total | Freq (%) |
|---|---|---|---|---|---|---|
| H333 | 5-1 | CASSLEGRPDHEQY | 2-7 | 5 | 23 | 21.74 |
| 2 | CASSYSQGGTEAF | 1-1 | 4 | 23 | 17.39 | |
| 11 | CASSPYTDTQY | 2-1 | 3 | 23 | 13.04 | |
| 6-5 | CASSYADEQY | 2-7 | 2 | 23 | 8.70 | |
| 2 | CASKEVAGGRYTGELF | 2-2 | 2 | 23 | 8.70 | |
| 7-8 | CASSFRGDPFYGTY | 1-2 | 2 | 23 | 8.70 | |
| 7-9 | CASSLLDRGGGSTIY | 1-3 | 2 | 23 | 8.70 | |
| H267 | 5-1 | CASSLAGGYSPLH | 1-6 | 9 | 67 | 13.43 |
| 4-1 | CASSRTTSSSYNEQF | 2-1 | 7 | 67 | 10.45 | |
| 2 | CASSDRGVGTGELF | 2-2 | 6 | 67 | 8.96 | |
| 6-5 | CASSYRTSQVINSPLH | 1-6 | 6 | 67 | 8.96 | |
| 19 | CASIKRTLPGASNTEAF | 1-1 | 6 | 67 | 8.96 | |
| 7-4 | CASSLFVSGDSPLH | 1-6 | 5 | 67 | 7.46 | |
| 12-3 | CASSPGLAGYEQF | 2-1 | 3 | 67 | 4.48 | |
| 27 | CASSSWDTDSPLH | 1-6 | 3 | 67 | 4.48 | |
| 24 | CASSLQGESGPLH | 1-6 | 3 | 67 | 4.48 | |
| 28 | CASSATGVIHNEQF | 2-1 | 2 | 67 | 2.99 | |
| 6-2 | CASSYGTQGQY | 2-7 | 2 | 67 | 2.99 | |
| 20-1 | CSARDLGDSNSPLH | 1-6 | 2 | 67 | 2.99 | |
| 4-2 | CASSGYRGGNQPQH | 1-5 | 2 | 67 | 2.99 | |
| H504 | 27 | CASSSGLIRF | 2-1 | 7 | 26 | 26.92 |
| 3-1 | CASSRDSGFKDTQY | 2-5 | 4 | 26 | 15.38 | |
| 5-5 | CASSLETRGTNEQF | 2-1 | 2 | 26 | 7.69 | |
| 2 | CASRVGTGAQPQH | 1-5 | 2 | 26 | 7.69 | |
| 5-1 | CASSLAGSGYGYT | 1-2 | 2 | 26 | 7.69 |