Table 1.
General characteristics of the GeneBank participants
| Caucasian | African American | |||||
|---|---|---|---|---|---|---|
| Without CAD (n = 913) | With CAD (n = 2,834) | p value | Without CAD (n = 263) | With CAD (n = 502) | p value | |
| Age (years) | 59 ± 12 | 66 ± 11 | <0.0001 | 57 ± 11 | 61 ± 11 | <0.0001 |
| Male/female (n) | 478/435 | 2,140/694 | <0.0001 | 99/164 | 264/238 | <0.0001 |
| BMI (kg/m2) | 29.7 ± 6.8 | 29.4 ± 5.6 | 0.92 | 33.6 ± 8.1 | 31.2 ± 7.1 | <0.0001 |
| Total cholesterol (mg/dl) | 177 ± 37 | 168 ± 40 | <0.0001 | 182 ± 38 | 176 ± 50 | 0.01 |
| HDL-cholesterol (mg/dl) | 42 ± 13 | 37 ± 11 | <0.0001 | 51 ± 15 | 46 ± 15 | <0.0001 |
| LDL-cholesterol (mg/dl) | 108 ± 31 | 100 ± 33 | <0.0001 | 111 ± 72 | 106 ± 43 | 0.13 |
| Triglycerides (mg/dl) | 129 ± 81 | 155 ± 105 | <0.0001 | 123 ± 81 | 128 ± 83 | 0.32 |
| CRP (mg/l) | 2.2 (3.4) | 3.1 (5.7) | <0.0001 | 2.2 (3.7) | 3.0 (5.6) | 0.008 |
| DBP (mmHg) | 75 ± 12 | 74 ± 12 | 0.004 | 81 ± 13 | 77 ± 13 | 0.0002 |
| SBP (mmHg) | 133 ± 20 | 135 ± 21 | 0.003 | 139 ± 22 | 140 ± 23 | 0.53 |
Data are shown as mean ± SD with the exception of CRP levels which are shown as median (IQR). Two-sided p values are reported between subjects with and without CAD at baseline