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Clonality analysis of lymphoma samples at diagnosis and relapse. Polymerase chain reaction (PCR) was performed using established Biomed-2 protocols and analyzed by capillary electrophoresis. An identical immunoglobulin heavy chain (IgH) gene rearrangement is identified in the lymphoma at initial diagnosis (upper) and at relapse (lower). PCR for framework region 1 (FR1) is shown. The scale indicates the size of the PCR product in base pairs.
