Table 1.
Relationship between the clinical-pathologic characteristics and PROM-1 expression levels of the 45 cases
| Characteristic |
No. (%) of patients | PROM1 expression | P | |
|---|---|---|---|---|
| Age, months | ||||
| <36 | 4 (8.9) | 4.39 (0.77–18.4) | .47 | |
| >36 | 41 (91.1) | 1.84 (0.06–257) | ||
| Sex | ||||
| Male | 30 (66.7) | 1.67 (0.06–257) | .74 | |
| Female | 15 (33.3) | 1.84 (0.26–38.3) | ||
| Period of diagnosis | ||||
| 1991–1996 | 18 (40) | 1.97 (0.16–257) | .74 | |
| 1997–2007 | 27 (60) | 1.45 (0.06–38.3) | ||
| Histological variant | ||||
| Classic | 35 (77.8) | 1.84 (0.06–257) | .05a | |
| LC/A | 4 (8.9) | 5.94 (2.52–23.8) | ||
| Desmoplastic | 6 (13.3) | 0.95 (0.26–3.99) | ||
| Nondesmoplastic (Classic + LC/A) | 39 (86.7) | 1.97 (0.16–257) | .09 | |
| Desmoplastic | 6 (13.3) | 0.95 (0.26–3.99) | ||
| M stage | ||||
| M0 | 29 (64.4) | 1.13 (0.06–38.3) | .03 | |
| M+ | 15 (33.4) | 2.56 (0.64–257) | ||
| NV | 1 (2.2) | |||
| Surgical resection | ||||
| Complete (<1.5 cm2 residual tumor) | 36 (80) | 2.04 (0.14–257) | .02 | |
| Partial (>1.5 cm2 residual tumor) | 9 (20) | 0.87 (0.06–2.56) | ||
| Relapse | ||||
| Yes | 23 (51.2) | 2.11 (0.06–257) | .10 | |
| No | 21 (46.6) | 1.07 (0.11–29.9) | ||
| NV | 1 (2.2) | |||
| Treatment | ||||
| CT or RT only | NOR | 7 (15.5) | 5.86 (0.77–23.8) | .15a |
| HDCT + RT | HD | 14 (31.2) | 1.09 (0.06–38.3) | |
| Standard CT + RT | SD | 24 (53.3) | 1.53 (0.16–257) | |
| Outcome | ||||
| Alive | 23 (51.1) | 1.05 (0.06–29.9) | .007 | |
| Died | 22 (48.9) | 3.46 (0.16–257) | ||
P values refer to Mann–Whitney U-test, unless otherwise specified. NV denotes that data not available; M0 denotes the absence of metastasis; M+ denotes the presence of metastasis; CT denotes chemotherapy; RT denotes radiotherapy; and HDCT denotes high-dose chemotherapy.
aKruskal–Wallis test