Table 1. iTRAQ data reveals increased secretion of several danger signal proteins, ras-related proteins, V-type proton ATPases and cathepsins in the influenza A virus infected macrophages.
| Protein name | Access No | Secretome | ||
| 6 h | 9 h | 12 h | ||
| Danger signal proteins | ||||
| Amyloid beta A4 protein | Q5IS80 | 2.1 | 1.8 | 2.8 |
| Galectin-3 | P17931 | 2.3 | 2.5 | 4.9 |
| High mobility group protein B1 | P09429 | 2.1 | 5.6 | 8.7 |
| High mobility group protein B2 | P26583 | 2.9 | 5.1 | 11.2 |
| Protein S100-A8 | P05109 | 1.8 | 2.0 | 3.3 |
| Protein S100-A9 | P06702 | 2.1 | 2.2 | 4.1 |
| Ras-related proteins | ||||
| Ras-related protein Rab-10 | P61026 | - | 5.8 | 12.6 |
| Ras-related protein Rab-11A | P62491 | - | 3.9 | 5.5 |
| Ras-related protein Rab-1A | P62820 | - | - | 4.5 |
| Ras-related protein Rab-2 | P61225 | - | - | 14.9 |
| V-type proton ATPases | ||||
| V-type proton ATPase catalytic subunit A | P38606 | 4.3 | 4.4 | 7.8 |
| V-type proton ATPase subunit B, brain isoform | P21281 | - | - | 11.9 |
| V-type proton ATPase subunit C | P21283 | 5.2 | 5.4 | 7.3 |
| V-type proton ATPase subunit D | Q9Y5K8 | - | - | 4.8 |
| V-type proton ATPase subunit E 1 | P36543 | 2.8 | 4.3 | 8.6 |
| V-type proton ATPase subunit G 1 | O75348 | 2.1 | 3.7 | 7.6 |
| Cathepsins | ||||
| Cathepsin B | P07858 | 1.1 | 1.1 | 2.2 |
| Cathepsin D | P07339 | 2.4 | 2.8 | 6.7 |
| Cathepsin H | P09668 | 2.2 | 2.7 | 5.7 |
| Cathepsin L2 | O60911 | 3.3* | 3.6* | 9.8* |
| Cathepsin S | P25774 | 1.5 | 1.6 | 3.3 |
| Cathepsin Z | Q9UBR2 | 1.5 | 1.5 | 3.0 |
Fold differences for the proteins are calculated as an average of both biological replicates.
*identified from only one biological replicate.