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. 2011 May 12;6(5):e19785. doi: 10.1371/journal.pone.0019785

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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A. Significant decrease in the total number of small intestinal polyps per mouse in 19 wk old APC^Min/+ mice that were placed in 10% versus 21% oxygen for 14 wk, starting at 5 wk of age. Data shown as mean ± SEM, with n = 12. B. Decreased smaller diameter polyps (black arrowheads) in representative intestinal segments from mice in 10% compared to 21% oxygen. C. Quantification of polyps classified by size (polyp diameter, mm) in 10% versus 21% oxygen. The relative reduction in polyp number in 10% versus 21% oxygen is greatest for the smallest diameter polyps (<1.5 mm). Data shown as mean ± SEM, with n = 12.