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. 2011 May 12;6(5):e19962. doi: 10.1371/journal.pone.0019962

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This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Frozen sections from 8 (N = 5), 12 (N = 5), 16 (N = 4), and 20 (N = 5) week old non-treated NOD SGs were analyzed and quantified for natural ICAM-1 expression. Representative images (400× magnification) of ICAM-1 expression in NOD SGs are shown at 8 (A), 12 (B), 16 (C), and 20 (D) weeks of age. Arrows indicate ICAM-1 expression at ductal and endothelial epithelium. E) Quantification of ICAM-1 expression for all ages. Data shown are mean values +/− SD. The P-value was determined by the parametric Student's t-test.