Fig. 1.

IECs express type I and III IFN genes after rotavirus challenge. Suckling C57BL/6 mice were orally infected with murine rotavirus strain EDIM (5 μL of 1:100 diluted virus stock). IECs were isolated at day 4 (n = 5) and day 11 (n = 5) postinfection (pi, black bars) or from uninfected control mice (open bars, n = 4) and analyzed by quantitative RT-PCR for expression of (A) Ifn-β, Ifn-λ2/3, and (B) Isg15 and Oasl2 genes. Results are representative for at least two independent experiments.