. Author manuscript; available in PMC: 2011 May 13.

Published in final edited form as: J Vaccines Vaccin. 2010 Aug 20;1(1):1000101. doi: 10.4172/2157-7560.1000101

Table 5.

The relative rank of the five tested HLA-A2.1 restricted epitopes from CRPV E1 is summarized from HLA-A2.1 transgenic mouse and rabbit system.

CRPV E1 Epitope	Mouse rank			Rabbit rank			Overall rank
	Mouse rank			Rabbit rank			In vitro		In vivo

	Tetramer binding		IFNγ assay	Tetramer and ⁵¹Cr	In vivo protection		Mouse	Rabbit	Rabbit
	Peptide vaccine	DNA vaccine	IFNγ assay	Tetramer and ⁵¹Cr	half dose	full dose	Mouse	Rabbit	Rabbit

42-50	NR	2	NR	NR	3	2	4	NR	3
149-157	NR	1	3	NR	2	1	3	NR	2
161-169	2	NT	2	2	4	2	2	2	4
245-253	NR	NR	NR	NR	4	2	NR	NR	4
303-311	1	NT	1	1	1	1	1	1	1

NR—Non-responder; NT-Not Tested