Table 2.

Summary of VBQ results within grey matter (p_FWE < 0.05), uncorrected results (p < 0.001) are highlighted with an asterisk. Coordinates [x y z] refer to the Montreal Neurological Institute (MNI) standard stereotactic space.

VBQ analysis	Region	Left hemisphere coordinates (mm)			t score	z score	Right hemisphere coordinates (mm)			t score	z score
x	y	z	x	y	z
FA GM
Age-positive correlation	middle cingulate						15	−16	43	5	4.8
hipp	−9	−39	3	6	5.7	12	−36	3	4.7*	4.5*
putamen	−24	3	−8	6.3	5.9	30	−4	−9	5.2	4.9
caudate	−17	−1	15	4.8*	4.6*	21	2	18	4.5*	4.4*
rACC	0	29	−14	4*	3.8*
FA GM
Age-negative correlation	caudate	−8	21	−5	4.2*	4.1*	10	23	−6	6.1	5.7
cerebellum V	−11	−48	−23	5.5	5.2	12	−46	−24	5.1	4.8
SNc	−14	−19	−9	5.9	5.6	15	−19	−9	6.2	5.8
MD GM
Age-positive correlation	S1	−27	−38	66	7.5	6.8	29	−35	66	6.5	6.1
thalamus habenula	−3	−25	0	7.9	7.1	3	−24	−3	6.9	6.4
thalamus MD	−9	−3	9	6.5	6.1	10	−6	12	5.7	5.4
M1	−30	−27	58	8.3	7.4	27	−26	66	6.7	6.2
operculum	−50	12	30	8.8	7.8
hypothalamus	−3	5	−14	6.6	6.2	6	5	−14	6.8	6.3
caudate	−8	14	4	5.7	5.4	10	17	6	7.4	6.7
precuneus						11	−69	27	7.3	6.6
cerebellum vermis	−3	−76	−27	7.1	6.5	4	−64	−9	11.8	Inf
MT GM
Age-negative correlation	S1	−21	−27	53	6	5.6	31	−28	48
caudal middle frontal						16	0	53
caudate	−17	−11	17	4.5*	4.4*	13	−6	16	7	6.4
M1	−17	−27	67	5.1	4.8	27	−24	66	6.9	6.4
putamen	−31	−23	3	4.2*	4.1*	28	−21	4	4.3*	4.2*
thalamus VL						16	−15	3	4.1*	4*
caudate	−15	−14	17	5.4*	4.3*	17	−12	19	4.7*	3.8*
cerebellum	−14	−56	−32	5.1	4.8	17	−55	−39	5.2	5
R2* GM
Age-positive correlation	SNc	−11	−13	−12	5.7	5.4	12	−12	−11	6	5.6
OFC	−2	30	−27	5.6	5.3
putamen	−27	−12	−2	12	Inf	28	−10	0	13.8	Inf
pallidum	−14	2	−5	8.7	7.7	13	2	−5	9.1	Inf
fusiform	−47	−16	−29	7.7	7	37	−13	−36	9.4	Inf
caudate	−18	−2	15	4.8*	4.6*	18	5	14	4.5*	4.3*

GM – grey matter; FA – fractional anisotropy; MD – mean diffusivity; MT – magnetization transfer; DLPFC – dorso-lateral prefrontal cortex; OFC – orbito-frontal cortex; rACC – rostral anterior cingulate cortex; M1 – primary motor cortex; S1 – primary somatosensory cortex; thalamus MD – thalamic medio-dorsal nucleus; thalamus VL – thalamic ventro-lateral nucleus; SNc – substantia nigra pars compacta; hipp – hippocampus.