Table. Goals of the AMPATH Cardiovascular and Pulmonary Disease Center of Excellence with Existing Strengths, Necessary Enhancements and Examples of Implementation for each goal.

Goal 1. Organize an administrative core for CVPD clinical care, training and research
Existing Strengths*	Desired Outcome	Implementation Examples
Experienced Research and Sponsored Projects Office Institutional Research and Ethics Committee Broad communications/conferencing platform	Long-term experience as primary grantee from the US NIH Collaboration between Institutional Review Boards	Twinning relationships between faculty and administrative staff counterparts of collaborating institutions Establish discipline specific working groups
Goal 2. Develop and implements a competency-based clinical training curriculum
Existing Strengths	Desired Outcome	Implementation Examples
23 Satellite clinic locations AMRS-facilitated feedback to clinicians regarding compliance with guidelines AMRS-facilitated feedback on patient outcomes	Cardiovascular and Pulmonary disease clinical expertise Advanced diagnostic and therapeutic services for chronic NCDs	“Train the Trainers” approach Target multiple levels of practitioner On-site and US-based training
Goal 3. Establish a CVPD clinical research training program
Existing Strengths	Desired Outcome	Implementation Examples
Extensive databank within the AMRS Track record of high-quality clinical research in HIV	Mentored clinical research experience for trainees in CVPD Certification in biostatistics and research ethics	Train physician and non-physician clinical-investigators Multi-dimensional mentoring framework Web-based curricula Kenyan and American mentors
Goal 4. Adopt and enhance AMPATH's existing data management and laboratory infrastructure and research network for CVPD
Existing Strengths	Desired Outcome	Implementation Examples
Standard Encounter Forms Certified Research Laboratory	CVPD-specific collection of clinical data CVPD relevant assays/tests	New CVPD-based encounter forms Enhancing CVPD diagnostic technology (e.g., echocardiography, spirometry)
Goal 5. Implement research programs to address prevalence, prevention and treatment of CVPD that afflict citizens of western Kenya
Existing Strengths	Desired Outcome	Implementation Examples
Large (>2 million person) catchment area International clinical research site for NIH's AIDS Clinical Trials Group	Data on CVPD epidemiology in western Kenya Addressing the “double burden” of CVPD in Kenya	Kenyan ownership of research goals Research goals also aligned with US (e.g., Institute of Medicine) and International (e.g., WHO) recommendations

^*These strengths are applicable across goals and are not limited in their utility to one specific goal