Table 3. SAR of Substitution on 5-Amino for ALK.
Antiproliferative activity (IC50, μM) on Tel-Alk-Ba/F3, EML4-Alk-Ba/F3, and parental Ba/F3 respectively; values are means of two experiments, and the standard deviation is less than 10% of means.
Antiproliferative activity (IC50, μM) on Tel-Alk-Ba/F3, EML4-Alk-Ba/F3, and parental Ba/F3 respectively; values are means of two experiments, and the standard deviation is less than 10% of means.