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. Author manuscript; available in PMC: 2011 May 13.
Published in final edited form as: Dev Dyn. 2009 Mar;238(3):595–603. doi: 10.1002/dvdy.21876

Fig. 5.

Fig. 5

Driving miRNA expression in the V6 lineage can repress egl-5 expression. A. The integrated egl-5 reporter gene bxIs13 is expressed in ray sublineages, male sex muscles, tail hypodermis, and PLM. B. A transgene containing the mir-56 gene under the control of the V6 lineage cis-regulatory element V6CRE blocks bxIs13 expression in the ray sublineages and PLM but not in sex muscles or tail hypodermis. C. Transgenes containing mir-56 and mir-247 under the control of V6CRE can block bxIs13 expression in the V6 lineage and also generate a ray-defective phenotype consistent with absence of chromosomal egl-5 gene expression. Transgenes designed to express three other mir genes did not. Expression data is given for three independently transformed lines. P values are for comparison to bxIs13.